"Zotz-Klimas Genetics Lab, MVZ Zotz Klimas"[submitter] AND "MSH2"[gene - ClinVar

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 91110	NM_000251.3(MSH2):c.490G>T (p.Gly164Trp)	MSH2 (G164W +1 more)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +2 more	GPathogenic/Likely pathogenic
Select item 91194	NM_000251.3(MSH2):c.742A>G (p.Lys248Glu)	MSH2 (K248E +1 more)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +5 more	GConflicting classifications of pathogenicity
Select item 140810	NM_000251.3(MSH2):c.775C>T (p.Pro259Ser)	MSH2 (P259S +1 more)	Single nucleotide variant (missense variant)	Lynch syndrome 1 +6 more	GConflicting classifications of pathogenicity
Select item 90669	NM_000251.3(MSH2):c.1447_1448del (p.Glu483fs)	MSH2 (E417fs +1 more)	Microsatellite (frameshift variant)	Lynch syndrome	GPathogenic
Select item 90855	NM_000251.3(MSH2):c.2009C>T (p.Pro670Leu)	MSH2 (P670L +1 more)	Single nucleotide variant (missense variant)	Lynch syndrome +7 more	GConflicting classifications of pathogenicity
Select item 216350	NM_000251.3(MSH2):c.2197G>A (p.Ala733Thr)	MSH2 (A733T +1 more)	Single nucleotide variant (missense variant)	MSH2-related condition +5 more	GConflicting classifications of pathogenicity
Select item 140785	NM_000251.3(MSH2):c.2576_2584del (p.Glu859_Gln861del)	MSH2	Deletion (inframe_deletion)	Lynch syndrome 1 +5 more	GConflicting classifications of pathogenicity

ClinVar